糖皮质激素诱导的股骨头骨坏死(GIONFH)是一种常见的衰弱性疾病，发生在青年和中年人。治疗早期GIONFH，核心减压和植骨是有效的措施。然而，理想的骨移植物应具有生物活性和生物力学特性。目前最常用的植骨材料效果不理想。
2018年2月27日，四川大学康鹏德作为通讯作者在Biomaterials Science（IF=7.59）在线发表题为“Enhanced bone defect repairing effects in glucocorticoid-induced osteonecrosis of the femoral head using a porousnano-lithium-hydroxyapatite/gelatin microsphere/erythropoietin composite scaffold”的研究论文，该研究发现Li-nHA/GM/rhEPO支架可同时上调Wnt和HIF-1/VEGF通路，促进成骨和血管生成，有利于GIONFH的修复。
但是，在2023年4月4日，该文章被撤回，主要原因是文章涉嫌图片重复使用。
作者发现文章中有一些图片错误，要求更正。出于对数据可靠性的考虑，为了保持科学记录的准确性，作者和编辑在协商后决定撤回这篇文章。图5、图13、图15、图16、图17和图18中的一些面板包含复制图像的部分，包括:In Fig. 5, a section of the ‘rhEPO + AKTi/Calcium node’ panel is duplicated in the ‘Blank control/Calcium node’ panel.In Fig. 13a, a section of the HE ‘Blank control/8 week’ panel is duplicated in the HE ‘Blank control/12 week’ panel.In Fig. 13b, a section of the Masson ‘Autogenous bone/8 week’ panel is duplicated in the Masson ‘Autogenous bone/12 week’ panel.In Fig. 15a, a section of the ALP ‘nHA/12 week’ panel is duplicated in the ALP ‘Li-nHA/12 week’ panel.In Fig 16b, a section of the CD31 ‘Autogenous bone/12 week’ panel is duplicated in the CD31 ‘Li-nHA/GMs/rhEPO/12 week’ panel.In Fig. 16b, a section of the CD31 ‘nHA/12 week’ panel is duplicated in the CD31 ‘Li-nHA/12 week’ panel.In Fig. 17, a section of the PI3K ‘nHA/6 week’ panel is duplicated in the AKT ‘Li-nHA/12 week’ panel.In Fig. 17, a section of the PI3K ‘Li-nHA/6 week’ panel is duplicated in the AKT ‘Li-nHA/6 week’ panel.In Fig. 17, a section of the PI3K ‘Blank control/6 week’ panel is duplicated in the AKT ‘Blank control/6 week’ panel.In Fig. 17, different sections of the PI3K ‘Li-nHA/GMs/rhEPO/12 week’ panel are duplicated in the AKT ‘Li-nHA/GMs/rhEPO/6 week’ and AKT ‘Li-nHA/GMs/rhEPO/12 week’ panels. Furthermore, another section of the AKT ‘Li-nHA/GMs/rhEPO/6 week’ panel is also duplicated in the PI3K ‘Li-nHA/GMs/rhEPO/6 week’ panel.In Fig. 17, a section of the PI3K ‘Autogenous bone/12 week’ panel is duplicated in the AKT ‘Autogenous bone/12 week’ panel.A section of the PI3K ‘nHA/12 week’ panel in Fig. 17 is duplicated in the AKT ‘nHA/6 week’ panel of Fig. 17 and in the β-catenin ‘nHA/12 week’ panel of Fig. 18.In Fig. 18, a section of the GSK-3β ‘nHA/12 week’ panel is duplicated in the β-catenin ‘Li-nHA/GMs/rhEPO/12 week’ panel.In Fig. 18, a section of the β-catenin ‘Li-nHA/6 week’ panel is duplicated in the β-catenin ‘Li-nHA/12 week’ panel.作者还通知编辑，图13a中用于HE ' Li-nHA/8Week'面板的图像是不正确的。
此外，许多蛋白印迹图的背景存在差异，包括图4中的PPAR-γ图、图9中的GSK-3β图和图19B中的PI3K图。作者无法提供可验证的原始数据来验证已发表的蛋白印迹数据。https://pubs.rsc.org/en/content/articlelanding/2023/BM/D3BM90030D
