科研星球

SCI论文的摘要部分常用句型

摘要对于一篇文章来说是非常重要的部分,它是一篇文章的浓缩与精华,所以写好摘要就是给文章打下良好的基础。而写出好的摘要,除了逻辑外,语言优美,句式多样也是构成优秀摘要的关键因素。


分享一些翻阅文献时看到的摘要中比较好的句式,可以根据自己的想法进行修改用到自己的文章中~


-1-

研究空白点的句式

1.Little is known regarding the functional role of Ars2 in cell proliferation and leukemogenesis of acute myeloid leukemia
2.However, our understanding of the importance of these molecules in cardiac fibrosis is limited.
3.However, the molecular mechanisms by which SNHG8 contributes to HCC remain elusive and merit exploration (当我们能找到实验中研究的主指标和疾病高度相关的文献时,可以用这个句子写研究空白点来体现我们的创新点).
4.But it is unclear what determines whether miR-146a is oncogenic or tumor suppressive and the molecular mechanisms are still largely unknown (能找到实验中研究的主指标和疾病高度相关的文献时,这个句子可以用来体现我们的创新点).
5.However, TAMs often occurs with unknown mechanisms (能找到实验中研究的主指标和疾病高度相关的文献时,可以将这个句子改为…..exerts effects on xx疾病 with unknown mechanisms).

-2-
介绍目的的句式
1.Hence, the aim of the present study was to investigate whether miR-23b affects IRI whilst attempting to elucidate the mechanisms by which the p53 signaling pathway is implicated in this process.
2.The aim of this study is to identify the expression level of circPVT1 in NSCLC and further investigate its functional relevance with NSCLC progression both in vitro and in vivo (当实验做了体内实验和体外实验时可以用both in vitro and in vivo,当只做了其中一方面实验时both in vitro and in vivo可以删除).
3.We aimed to study the involvement of circZMYM2 (hsa_circ_0099999) in pancreatic cancer (PC) cell proliferation, apoptosis and invasion and to figured out the underlying mechanism of circZMYM2 regulating miR-335-5p and JMJD2C.
4.We aimed to explore key miRNAs and associated mechanisms by which breast cancer develops chemoresistance.
5.The aim of our study was to identify new targets regulated by miR-486-5p in RCC, to obtain a deeper insight into the network and to better understand the role of these microRNAs and their targets in carcinogenesis of RCC (用于研究miR靶向某个基因调控疾病的课题中).
6. The purpose of our study was to investigate the effects of the long noncoding RNA (lncRNA) ABHD11-AS1 on colorectal cancer (CRC) progression and further explore its possible underlying mechanisms.
7.In this study, we aimed at its functions and molecular mechanism in ovarian cancer progression.
8.Accordingly, the aim of the present study was to identify the expression patterns of EREG from an AMI perspective in an attempt to examine its effects on AMI with an emphasis placed on angiogenesis and left ventricular remodeling.

-3-

分组的句式

1. Loss- and gain-of-function investigations were conducted in rats treated with prolonged cold ischemia and polymorphonuclear neutrophils (PMNs). (Loss- and gain-of-function就是我们实验中的对某个因子的上调下调,沉默)
2.The functional role of miR-134 in HNSCC pathogenesis was determined using ectopic expression, knockdown/depletion and reporter assay experiments. (在研究miR靶向某个基因的实验中,摘要里可以用这个句子概括分组和双荧光素酶报告基因检测,ectopic expression, knockdown/depletion experiments代表基因的上调下调实验,reporter assay experiments代表的是双荧光素酶报告基因检测)
3.DA neurons were subjected to a series of inhibitors, activators and shRNAs to validate the mechanisms of miR-128 in controlling of AXIN1 in PD (摘要部分的分组也可以直接成对细胞进行了什么样的处理).
4.Further, the impact of increased and decreased miR-146a expression levels on the expression of predicted target genes, cell migration, viability, proliferation, and apoptosis was examined, respectively (这个句子概括了分组和分组后所进行的实验,the impact of increased and decreased miR-146a expression levels代表了实验中对miR-146a人为的进行上调下调,也就是实验中的分组处理).
5.The effects of NORAD on HCC cell malignant potential were investigated via NORAD overexpression and knockdown both in vitro and in vivo.
6.Moreover, to explore the role of miR-424-3p in NSCLC cells, miR-424-3p was re-expressed and knocked down using transient transfection with mimics and inhibitors.
7.miR-23b mimics or inhibitors were applied for the elevation or the depletion of the miR-23b expression and siRNA-MDM4 for the depletion of the MDM4 expression in the articular chondrocytes (比较简单也是比较具体的分组表达,直接说明了在什么细胞中用某种质粒或模拟物来上调下调某个基因).
8.in order to evaluate the effects of miR-1182 and miR-let-7a on cellular process, we performed a series of in vitro and in vivo experiments, delivering plasmids into QBC939 cell line to alter the expression of miR-1182, miR-let-7a, and NUAK1.
9.To elucidate the biological significance behind the physiological silencing of EREG and the regulatory mechanism between EREG and ERK1/2 signaling pathway, rat AMI models were established and treated with siRNA against EREG or an ERK1/2 pathway inhibitor PD98059, or both (用于基因沉默课题的摘要分组处理).

-4-

总结结论的句式

1.Together, our findings identify Wisper as a cardiac fibroblast-enriched super-enhancer-associated lncRNA that represents an attractive therapeutic target to reduce the pathological development of cardiac fibrosis in response to MI and prevent adverse remodeling in the damaged heart (这个句子是将结论和临床意义写成了一句,当实验研究的是一个因子对于某个疾病中细胞的增殖凋亡迁移侵袭的作用时,由于摘要的结果部分中已经一一写出细胞的增殖凋亡迁移侵袭的变化了,那摘要的结论部分就只需要做一个总结,那就可以直接用这个句子).
2.As lncRNA SNHG8 may promote HCC tumorigenesis and metastasis by sponging miR-149, it is a potential candidate marker and therapeutic target for HCC (结论和临床意义结合一起写).
3.Functional studies showed that miR-146a acts as a tumor suppressor miR and identifies miR-146a as a candidate for antimetastatic miRNA replacement therapy for gastric cancer patients.
4.This study suggested that HOXC13-AS exerted oncogenic function in NPC via regulating miR-383-3p/HMGA2 axis.
5.the key findings of the present study provided evidence that functional suppression of EREG enhances angiogenesis and prevents left ventricular remodeling by disrupting the ERK1/2 signaling pathway.
6.Based on the results observed during this study, it quickly became apparent that aligning the tibial component to the medial 1/3 of the tubercle could ultimately result in reduction of the incidence of rotational misalignment during TKA procedures.

-5-

临床意义的句式

1. These findings may open new avenues of research to harness the role of miR-21-5p in optimizing future stem cell-based cardiotherapies.

2. These findings provide mechanistic insight of unrecognized roles of TUSC3 in cancer progression.

3. Therefore, silence of circPVT1 could be a future direction to develop a novel treatment strategy.

4. Thus, miR-128 may serve as a potential target for the treatment of PD.

5. This study provides new insights to develop effective interventions for cancer patients with acquired resistance to chemotherapy.

6. The study demonstrates that there are potential diagnosis and therapy values of miR-486-5p in RCC.

7. which provide basic therapeutic considerations for a novel target against IRI.

8. The finding obtained from the study provides an enhanced understanding of miRNA as a therapeutic target to limit (此语句可适用于miRNA或lncRNA文章的临床意义描述)progressive VC in hyperphosphatemia of CKD.


-6-

复合组结果的表达

拯救实验(rescue assays, 即复合结果的表达)
1. The absence of the effects of miR-23b was observed after MDM4 knocked down.
2. miR-133a-3p reversed such adverse effects by regulating COL1A1 (摘要部分如果是写的靶基因带来的影响时,可以用这个句子表明miR的作用).
3. PD98059 was determined to enhance the preventive effects of EREG inhibition on AMI (某种处理能增强某个基因对疾病的作用,但是得根据实验中的分组及相关结果写).



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