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「电子书」Experimental Design for Biologists 生物学家的实验设计 PDF

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科学实验的有效设计是成功的关键,但研究生在如何做实验方面接受的正式培训却很少。基于作者教授的一门广受好评的课程,《生物学家的实验设计》填补了这一空白。生物学家的实验设计》解释了如何建立一个实验项目的框架,如何建立一个系统,在该系统中设计实验,以及如何确定和使用正确的对照组。分别有几章专门讨论阴性对照、阳性对照和其他可能不太被认可的对照类别,如 "假设对照 "和 "实验者对照"。此外,还有关于建立实验系统的章节,其中包括执行关键的 "系统控制"。所有的实验计划都应该是假设驱动的吗?问题/答案的方法是否更合适?人类基因组计划背后的假说是什么?天空是什么颜色?怎样才能到达卡内基音乐厅?这类问题的答案可以在《生物学家的实验设计》中找到。该书以一种引人入胜的方式,提供了令人信服的课程,涉及到如何构建一个实验问题,建立一个有效的系统来回答这个问题,以及从实验数据中得出可验证的模型。《生物学家的实验设计》是设计研究计划时理论和实践指导的重要来源。


The effective design of scientific experiments is critical to success, yet graduate students receive very little formal training in how to do it. Based on a well-received course taught by the author, Experimental Design for Biologists fills this gap. Experimental Design for Biologists explains how to establish the framework for an experimental project, how to set up a system, design experiments within that system, and how to determine and use the correct set of controls. Separate chapters are devoted to negative controls, positive controls, and other categories of controls that are perhaps less recognized, such as "assumption controls," and "experimentalist controls." Furthermore, there are sections on establishing the experimental system, which include performing critical "system controls." Should all experimental plans be hypothesis-driven? Is a question/answer approach more appropriate? What was the hypothesis behind the Human Genome Project? What color is the sky? How does one get to Carnegie Hall? The answers to these kinds of questions can be found in Experimental Design for Biologists. Written in an engaging manner, the book provides compelling lessons in framing an experimental question, establishing a validated system to answer the question, and deriving verifiable models from experimental data. Experimental Design for Biologists is an essential source of theory and practical guidance in designing a research plan.Related Titles from the Publisher Statistics at the Bench: A Step-By-Step Handbook for Biologists CSH Protocols Laboratory Research Notebook


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