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「电子书」3D cell culture : fundamentals and applications in tissue engineering and regenerative medicine 3D细胞培养: 组织工程和再生医学的基础和应用 PDF

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三维细胞培养还没有被采用,也没有被充分挖掘其潜力。它有望将我们对人类生理学的理解提升到最高水平,并将这些知识应用于更好的诊断以及治疗的范围。本书的重点是新技术的直接影响,并将其演化为造福人类的可行产品。它还描述了细胞微环境的基本原理,以提出3D细胞培养在组织工程和再生医学中的相关性。它讨论了细胞外基质/微环境(ECM),并强调其对3D细胞生长的意义,以完成生理上可行的细胞质量/组织的体外培养。本书通过图文并茂的方式弥补了医学需求和技术应用之间的知识鸿沟。它讨论了现有的3D细胞培养模型,以及创建基质和支架以实现所需3D微环境的技术。


3D cell culture is yet to be adopted and exploited to its full potential. It promises to upgrade and bring our understanding about human physiology to the highest level with the scope of applying the knowledge for better diagnosis as well as therapeutics. The focus of this book is on the direct impact of novel technologies and their evolution into viable products for the benefit of human race. It also describes the fundamentals of cell microenvironment to bring forth the relevance of 3D cell culture in tissue engineering and regenerative medicine. It discusses the extracellular matrix/microenvironment (ECM) and emphasizes its significance for growing cells in 3D to accomplish physiologically viable cell mass/tissue ex vivo. The book bridges the knowledge gaps between medical need and the technological applications through illustrations. It discusses the available models for 3D cell culture as well as the techniques to create substrates and scaffolds for achieving desired 3D microenvironment.

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