本卷深入探讨了干细胞、外植体和其他微囊在生物功能和分子机制中的关键作用，以及它们在转化纳米医学中的治疗潜力。它进一步强调了最近研究的证据，说明干细胞衍生的外泌体和microRNAs如何恢复和维持组织平衡，使细胞恢复关键的细胞功能并开始修复再生。这些在动物衰老模型中的早期研究也显示了免疫、心血管和认知功能的改善，以及健康期和寿命的延长。利用体液中的外泌体来定义各种肿瘤的特异性生物标志物，也可以通过开发外泌体衍生的基于microRNA的癌症治疗药物，为患者的靶向治疗扫清道路。本书是学术界或制药或生物技术行业的研究生、研究员和生物医学研究人员的必备读物。

This volume provides insight into the pivotal roles of stem cells, exosomes and other microvesicles in biofunction and molecular mechanisms and their therapeutic potential in translational nanomedicine. It further highlights evidence from recent studies as to how stem cell derived exosomes and microRNAs may restore and maintain tissue homeostasis, enable cells to recover critical cellular functions and begin repair regeneration. These early studies in animal models of aging also show evidence of improved immune, cardiovascular and cognitive functions as well as improved health span and life span. The use of exosomes from body fluids to define specific biomarkers for various tumors may also clear the path to patient-targeted treatments by developing exosome-derived microRNA based cancer therapeutics. It is essential reading for graduate students, research fellow and biomedical researchers in academia or the pharmaceutical or biotech industries.