Harrison’s Principles of Internal Medicine, Twentieth Edition (Vol.1 & Vol.2) 哈里森的《内科学原理》第二十版（第1卷和第2卷）英文原版PDF
介紹具有里程碑意義的《全球內科標誌》第二十版。
这本内科权威指南比以往任何时候都要重要，它包含了最新的疾病机制、更新的临床试验结果和推荐指南、最先进的放射图像、治疗方法和具体治疗方法、数百张示范性全彩图，以及实用的临床决策树和算法。
哈里森的《内科医学原理》被全世界的医疗保健专业人士公认为是应用病理生理学和临床医学方面的权威，它为您提供了提供最佳病人护理所需的信息基础。
这本具有里程碑意义的第20版对实践和教育都是必不可少的。
彻底修订的内容--涵盖了自上一版Harrison's以来临床医学的许多新突破和新进展。有关急性和慢性肝炎、糖尿病管理、癌症中的免疫疗法、多发性硬化症、心血管疾病、HIV等章节，提供了有关疾病机制、诊断选择和具体治疗指导的最新信息，您需要提供最佳的患者护理。
最先进的疾病机制：Harrison's以严谨的态度专注于病理生理学，目标是将疾病机制与治疗联系起来。改善对疾病如何发展和进步的理解，不仅能促进更好的决策和更高价值的护理，还能使阅读引人入胜，提高记忆力.Harrison's总结了重要的基础科学新进展，如线粒体在细胞程序性死亡和坏死中的作用，免疫系统在癌症发展和治疗中的作用，端粒缩短在衰老和疾病过程中的影响，以及微生物组在健康和疾病中的作用。理解炎症在心血管疾病中的作用，了解免疫缺陷在HIV/AIDS中的精确机制，了解朊病毒和错误折叠蛋白在神经退行性疾病中的作用，了解肥胖是糖尿病的诱发因素，这些只是本版为卫生专业人员提供基本病理生理学信息的几个例子。
全新的章节涵盖了所有医护人员感兴趣的广泛的新领域和新兴领域。医学中的性别和基于性别的问题；肥胖症、糖尿病和代谢综合征；以及咨询医学--另外，新的部分涵盖了研究和临床医学的前沿话题，包括关于表观遗传学在健康和疾病中的作用、改善健康的行为策略、基因组学和传染病、新兴的神经治疗技术、健康和疾病中的端粒功能以及网络系统医学的新章节。
重要而及时的新章节--如促进良好健康、LGBT健康、医疗系统、医疗咨询方法、药物基因组学、抗菌素耐药性、世界范围内感染性疾病模式的变化、神经脊髓炎等--就医学教育和实践中必须知道的主题提供了最新的、权威的观点。
更新的临床指南、专家意见和来自世界著名编辑和作者的治疗方法都有助于提高教材的准确性和即时性，并为优化患者治疗效果提供了清晰的蓝图。
章末建议阅读内容强化了文字材料，并为进一步学习和研究提供了强大的平台。
MASTER MODERN MEDICINE!
Introducing the Landmark Twentieth Edition of the Global Icon of Internal Medicine
The definitive guide to internal medicine is more essential than ever with the latest in disease mechanisms, updated clinical trial results and recommended guidelines, state-of-the art radiographic images, therapeutic approaches and specific treatments, hundreds of demonstrative full-color drawings, and practical clinical decision trees and algorithms
Recognized by healthcare professionals worldwide as the leading authority on applied pathophysiology and clinical medicine,Harrison's Principles of Internal Medicinegives you the informational foundation you need to provide the best patient care possible.
Essential for practice and education, the landmark 20th Edition features:
Thoroughly revised content--covering the many new breakthroughs and advances in clinical medicine that have occurred since the last edition ofHarrison's. Chapters on acute and chronic hepatitis, management of diabetes, immune-based therapies in cancer, multiple sclerosis, cardiovascular disease, HIV, and many more, deliver the very latest information on disease mechanisms, diagnostic options, and the specific treatment guidance you need to provide optimal patient care.
State-of-the-art coverage of disease mechanisms:Harrison'sfocuses on pathophysiology with rigor, and with the goal of linking disease mechanisms to treatments. Improved understanding of how diseases develop and progress not only promotes better decision-making and higher value care, but also makes for fascinating reading and improved retention.Harrison'ssummarizes important new basic science developments, such as the role of mitochondria in programmed and necrotic cell death, the immune system's role in cancer development and treatment, the impact of telomere shortening in the aging and disease processes, and the role of the microbiome in health and disease. Understanding the role of inflammation in cardiovascular disease, the precise mechanisms of immune deficiency in HIV/AIDS, prions and misfolded proteins in neurodegenerative diseases, and obesity as a predisposition to diabetes are just a few examples of how this edition provides essential pathophysiology information for health professionals.
All-new sections covering a wide range of new and emerging areas of vital interest to all healthcare professionals.New sections include: Sex and Gender-based Issues in Medicine; Obesity, Diabetes Mellitus, and Metabolic Syndrome; and Consultative Medicine-- Plus, a new Part covering cutting-edge topics in research and clinical medicine includes great new chapters on the role of Epigenetics in Health and Disease, Behavioral Strategies to Improve Health, Genomics and Infectious Diseases, Emerging Neuro-Therapeutic Technologies, and Telomere Function in Health and Disease, and Network System Medicine.
Important and timely new chapters--such as Promoting Good Health, LGBT Health, Systems of Healthcare, Approach to Medical Consultation, Pharmacogenomics, Antimicrobial Resistance, Worldwide Changes in Patterns of Infectious Diseases, Neuromyelitis Optica, and more--offer the very latest, definitive perspectives on must-know topics in medical education and practice.
Updated clinical guidelines, expert opinions, and treatment approaches from world-renowned editors and authorscontribute to the accuracy and immediacy of the text material and present a clear blueprint for optimizing patient outcomes.
End-of-chapter suggested readingsreinforce the text material and provide a robust platform for further study and research.
